Stevens-Johnson syndrome

{
  "id": "MLC-T-CHM-011406",
  "term": "Stevens-Johnson syndrome",
  "field": "Chemistry",
  "definition": "A rare, severe mucocutaneous reaction, most often triggered by drugs such as allopurinol, anticonvulsants, sulfonamide antibiotics, and nevirapine, with painful blistering and detachment of skin and mucous membranes. It is a medical emergency because of the risk of infection, fluid loss, and organ damage. It lies on a spectrum with toxic epidermal necrolysis, and skin detachment under 10% of body surface area defines the Stevens-Johnson end.",
  "synonyms": [
    "bullous erythema multiforme"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "allergic",
    "adverse drug reaction",
    "mucosa"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1247 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/stevens-johnson-syndrome/"
}