Azlactones

{
  "id": "MLC-T-CHM-012912",
  "term": "Azlactones",
  "field": "Chemistry",
  "definition": "Oxazol-5(4H)-ones, five-membered heterocycles with a ring oxygen, a ring nitrogen, and a lactone-type carbonyl, formed by cyclodehydration of N-acyl alpha-amino acids. They are activated acyl derivatives, which makes them useful in the Erlenmeyer-Plochl synthesis of amino acids from aldehydes and acylglycines. They are also the intermediates through which the C-terminal residue can racemize during some peptide couplings.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "carboxylic acids",
    "cyclization"
  ],
  "references": [
    "PAC, 1995, 67, 1307. 'Glossary of class names of organic compounds and reactivity intermediates based on structure (IUPAC Recommendations 1995)' on page 1321 (https://doi.org/10.1351/pac199567081307)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/azlactones/"
}