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CA1-pyramidal cell

Term · Chemistry · MLC-T-CHM-001559

A type of principal neuron located in the Cornu Ammonis 1 (CA1) field of the hippocampus in the brain. These cells receive major excitatory input from the CA3-pyramidal cells via the Schaffer collateral pathway and project primarily to the subiculum and entorhinal cortex. Due to their specific connectivity and receptor profile, CA1-pyramidal cells are particularly vulnerable to damage from ischemia and excitotoxicity.

Table 1. Record
IdentifierMLC-T-CHM-001559
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 854 (https://doi.org/10.1515/pac-2015-0103)
See alsoCA3-pyramidal cell; Cornu ammonis
Record as JSON
{
  "id": "MLC-T-CHM-001559",
  "term": "CA1-pyramidal cell",
  "field": "Chemistry",
  "definition": "A type of principal neuron located in the Cornu Ammonis 1 (CA1) field of the hippocampus in the brain. These cells receive major excitatory input from the CA3-pyramidal cells via the Schaffer collateral pathway and project primarily to the subiculum and entorhinal cortex. Due to their specific connectivity and receptor profile, CA1-pyramidal cells are particularly vulnerable to damage from ischemia and excitotoxicity.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CA3-pyramidal cell",
    "cornu ammonis"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 854 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/ca1-pyramidal-cell/"
}

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