Pyramidal inversion

{
  "id": "MLC-T-CHM-009694",
  "term": "Pyramidal inversion",
  "field": "Chemistry",
  "definition": "A dynamic process where a trigonal pyramidal molecule or a chiral center with a lone pair rapidly interconverts between two enantiomeric forms. This inversion occurs through a planar transition state, effectively flipping the pyramid. Nitrogen atoms in amines often undergo rapid pyramidal inversion at room temperature.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "apex current",
    "central atom",
    "enantiomer",
    "inversion",
    "ligands",
    "polytopal rearrangement"
  ],
  "references": [
    "PAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2215 (https://doi.org/10.1351/pac199668122193)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pyramidal-inversion/"
}