Clonal deletion

{
  "id": "MLC-T-CHM-002127",
  "term": "Clonal deletion",
  "field": "Chemistry",
  "definition": "A process in immunology where self-reactive lymphocytes are eliminated during their development to prevent autoimmune responses. This mechanism removes immune cells that would otherwise attack the body's own tissues. It is a key aspect of immune tolerance, occurring primarily in the thymus for T cells and in the bone marrow for B cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1145 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/clonal-deletion/"
}