Co-drug

{
  "id": "MLC-T-CHM-002168",
  "term": "Co-drug",
  "field": "Chemistry",
  "definition": "Two drugs joined by a chemical linkage into one molecule, usually with synergistic or complementary actions, so that the pair is delivered together and each partner can improve the delivery properties of the other. After administration the linkage is cleaved in the body, by enzymes or chemically, to release both active drugs. A co-drug is also called a mutual prodrug, in contrast to a carrier-linked prodrug, whose carrier has no activity of its own.",
  "synonyms": [
    "mutual prodrug [1]"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1731 (https://doi.org/10.1351/PAC-REC-12-11-23)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/co-drug/"
}