Macromolecular prodrug

{
  "id": "MLC-T-CHM-006876",
  "term": "Macromolecular prodrug",
  "field": "Chemistry",
  "definition": "A prodrug where the active drug molecule is covalently attached to a polymer carrier, designed to improve its pharmacokinetic properties or targeting. The polymer acts as a delivery system, often enhancing solubility, reducing toxicity, or prolonging circulation time. The active drug is released from the polymer in vivo.",
  "subject": "Polymer",
  "see_also": [
    "prodrug"
  ],
  "references": [
    "PAC, 2012, 84, 377. 'Terminology for biorelated polymers and applications (IUPAC Recommendations 2012)' on page 400 (https://doi.org/10.1351/PAC-REC-10-12-04)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/macromolecular-prodrug/"
}