Cyclopia

{
  "id": "MLC-T-CHM-002827",
  "term": "Cyclopia",
  "field": "Chemistry",
  "definition": "A rare and severe congenital abnormality resulting from the failure of the embryonic forebrain to divide into two hemispheres, a condition known as holoprosencephaly. This developmental defect leads to the formation of a single, centrally located eye or a partially fused eye socket. Cyclopia is incompatible with life and is associated with other profound craniofacial malformations, such as the absence of a nose or the presence of a proboscis-like structure above the eye.",
  "synonyms": [
    "cyclocephaly",
    "synophthalmia"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "congenital",
    "fossa",
    "holoprosencephaly",
    "orbit",
    "prosencephalon"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 741 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cyclopia/"
}