Desensitization

{
  "id": "MLC-T-CHM-013032",
  "term": "Desensitization",
  "field": "Chemistry",
  "definition": "A reduction in the responsiveness of a biological system to a continuous or repeated stimulus. This can occur at the cellular level, where receptors become less sensitive to their ligands, or at the organismal level, such as a decrease in allergic reactions after repeated exposure to an allergen. The process often involves changes in receptor number, affinity, or signaling pathway components.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1157 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/desensitization/"
}