Desymmetrization step

{
  "id": "MLC-T-CHM-003075",
  "term": "Desymmetrization step",
  "field": "Chemistry",
  "definition": "A chemical transformation that converts a molecule possessing a plane or center of symmetry into a chiral molecule. This process involves differentiating between enantiotopic or diastereotopic groups or faces within the symmetrical starting material. An example is the selective functionalization of one identical group in a meso compound to create a stereocenter.",
  "subject": "Organic and Biomolecular Chemistry",
  "references": [
    "PAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2205 (https://doi.org/10.1351/pac199668122193)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/desymmetrization-step/"
}