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Desymmetrization

Term · Chemistry · MLC-T-CHM-003074

A chemical transformation that converts a achiral molecule or a symmetrical chiral molecule into a chiral molecule with a lower degree of symmetry. This process often involves the selective modification of one of several equivalent functional groups or faces in a prochiral substrate. It is a key strategy in asymmetric synthesis for generating enantiomerically enriched compounds.

Table 1. Record
IdentifierMLC-T-CHM-003074
FieldChemistry
SubjectOrganic and Biomolecular Chemistry
ReferencesPAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2205 (https://doi.org/10.1351/pac199668122193)
See alsoChiral; Chirality; Inversion; Prochirality
Record as JSON
{
  "id": "MLC-T-CHM-003074",
  "term": "Desymmetrization",
  "field": "Chemistry",
  "definition": "A chemical transformation that converts a achiral molecule or a symmetrical chiral molecule into a chiral molecule with a lower degree of symmetry. This process often involves the selective modification of one of several equivalent functional groups or faces in a prochiral substrate. It is a key strategy in asymmetric synthesis for generating enantiomerically enriched compounds.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "chiral",
    "chirality",
    "inversion",
    "prochirality"
  ],
  "references": [
    "PAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2205 (https://doi.org/10.1351/pac199668122193)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/desymmetrization/"
}

Record 3,272 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.