Prochirality

{
  "id": "MLC-T-CHM-009495",
  "term": "Prochirality",
  "field": "Chemistry",
  "definition": "A geometric property of an achiral molecule or center that can be converted into a chiral one in a single substitution or addition step. An achiral trigonal planar center with three different attached groups is prochiral because adding a new group creates a chiral tetrahedral center. The two faces of the planar structure are designated 'Re' and 'Si' based on the Cahn-Ingold-Prelog priority rules of the attached groups.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "chiral",
    "chirality centre",
    "desymmetrization",
    "diastereoisomerism",
    "diastereotopic",
    "enantiotopic",
    "stereoheterotopic"
  ],
  "references": [
    "PAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2213 (https://doi.org/10.1351/pac199668122193)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/prochirality/"
}