Dominant half life

{
  "id": "MLC-T-CHM-003375",
  "term": "Dominant half life",
  "field": "Chemistry",
  "definition": "The half-life of a substance in a particular organ or compartment, chosen because it approximately defines the overall clearance rate of the substance at a given time. When elimination is multiphasic, it is the half-life of the phase that dominates clearance at that time, such as the slow terminal phase at late times, and it sets how long the substance persists in the body.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1208 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/dominant-half-life/"
}