Metabolic half-life

{
  "id": "MLC-T-CHM-007237",
  "term": "Metabolic half-life",
  "field": "Chemistry",
  "definition": "The period in which metabolism alone converts half of the amount of a compound present in an organism, leaving loss by excretion out of account. It equals the elimination half-life only when metabolism is the sole route of clearance. Metabolic stability assays with liver microsomes or hepatocytes estimate it from the decline of the parent compound over time.",
  "synonyms": [
    "metabolic half-time"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2004, 76, 1033. 'Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003)' on page 1059 (https://doi.org/10.1351/pac200476051033)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/metabolic-half-life/"
}