Metabolic transformation

{
  "id": "MLC-T-CHM-007240",
  "term": "Metabolic transformation",
  "field": "Chemistry",
  "definition": "The chemical alteration of a substance within a living organism, primarily through enzymatic reactions, to facilitate its excretion or modify its biological activity. This process, also known as biotransformation, converts lipophilic compounds into more polar, water-soluble metabolites. The liver is the primary organ for metabolic transformation, although other tissues also contribute.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1259 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/metabolic-transformation/"
}