Draize test

{
  "id": "MLC-T-CHM-003431",
  "term": "Draize test",
  "field": "Chemistry",
  "definition": "A controversial acute toxicity test developed in 1944 to assess the irritancy of substances on the skin or eyes of animals, typically rabbits. In the ocular Draize test, a substance is applied to one eye, and the effects are observed over several days. Due to ethical concerns, alternative in vitro methods are increasingly being developed and adopted.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1159 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/draize-test/"
}