Pyrogen test

{
  "id": "MLC-T-CHM-009703",
  "term": "Pyrogen test",
  "field": "Chemistry",
  "definition": "A biological assay performed to detect the presence of pyrogenic substances in pharmaceutical products, medical devices, or other materials intended for parenteral administration. The test typically involves injecting a sample into rabbits and monitoring their body temperature for an increase. A common alternative is the Limulus amoebocyte lysate (LAL) assay for bacterial endotoxins.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Limulus test",
    "endotoxin",
    "interleukin",
    "pyrogen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1237 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pyrogen-test/"
}