Electron-transfer dissociation

{
  "id": "MLC-T-CHM-003764",
  "term": "Electron-transfer dissociation",
  "field": "Chemistry",
  "definition": "A fragmentation method in mass spectrometry where a radical anion transfers an electron to a protonated peptide or protein, leading to the dissociation of peptide bonds. This process generates c- and z-type fragment ions, which retain post-translational modifications. It is particularly effective for analyzing large biomolecules and their modifications.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "proteomics"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1155 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/electron-transfer-dissociation/"
}