Epoxide hydrolase

{
  "id": "MLC-T-CHM-004047",
  "term": "Epoxide hydrolase",
  "field": "Chemistry",
  "definition": "An enzyme that catalyzes the hydrolysis of epoxides, converting them into corresponding trans-dihydrodiols. These enzymes are involved in the detoxification of xenobiotics and the metabolism of endogenous compounds, often converting reactive electrophilic epoxides into less reactive and more water-soluble products. Mammalian epoxide hydrolases are classified into microsomal and soluble forms.",
  "synonyms": [
    "epoxide hydratase"
  ],
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 751 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/epoxide-hydrolase/"
}