Exchange spectroscopy

{
  "id": "MLC-T-CHM-004171",
  "term": "Exchange spectroscopy",
  "field": "Chemistry",
  "definition": "A two-dimensional nuclear magnetic resonance (NMR) experiment designed to detect chemical or conformational exchange processes between different molecular sites. It involves a mixing period during which magnetization can be transferred between nuclei that are undergoing exchange. The presence of cross-peaks in the 2D spectrum indicates that nuclei are exchanging between distinct environments.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "nuclear Overhauser effect spectroscopy",
    "nuclear magnetic resonance spectroscopy"
  ],
  "references": [
    "PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 687 (https://doi.org/10.1515/pac-2019-0203)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/exchange-spectroscopy/"
}