Granulocyte colony-stimulating factor

{
  "id": "MLC-T-CHM-013136",
  "term": "Granulocyte colony-stimulating factor",
  "field": "Chemistry",
  "definition": "A glycoprotein that promotes the proliferation and differentiation of hematopoietic stem cells into granulocytes, a category of white blood cells. Produced by several cell types, including endothelial cells and macrophages, it specifically enhances the production of neutrophils from bone marrow precursors. Recombinant forms of this factor are used therapeutically to treat neutropenia, a condition characterized by a low count of neutrophils.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "bone marrow",
    "neutrophil"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1171 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/granulocyte-colony-stimulating-factor/"
}