Hershberger bioassay

{
  "id": "MLC-T-CHM-005223",
  "term": "Hershberger bioassay",
  "field": "Chemistry",
  "definition": "A standardized in vivo assay used to detect the androgenic or antiandrogenic activity of chemical substances. Castrated male rats are treated with the test compound, and the weights of androgen-sensitive accessory sex organs, such as the ventral prostate and seminal vesicles, are measured. An increase in organ weight indicates androgenic activity, while a decrease suggests antiandrogenic effects.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "androgenic"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 764 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hershberger-bioassay/"
}