HN(CO)CA

{
  "id": "MLC-T-CHM-013155",
  "term": "HN(CO)CA",
  "field": "Chemistry",
  "definition": "A three-dimensional nuclear magnetic resonance spectroscopy experiment that correlates the chemical shift of an amide proton and its attached nitrogen with the alpha carbon of the preceding amino acid residue. Magnetization is transferred from the amide proton to its nitrogen, then across the peptide bond to the preceding carbonyl carbon, and finally to the preceding alpha carbon. This experiment provides sequential assignment information by linking adjacent residues in a polypeptide chain.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "three-dimensional nuclear magnetic resonance spectroscopy"
  ],
  "references": [
    "PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 692 (https://doi.org/10.1515/pac-2019-0203)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/hn-co-ca/"
}