Immune complex disease

{
  "id": "MLC-T-CHM-005637",
  "term": "Immune complex disease",
  "field": "Chemistry",
  "definition": "A condition resulting from the deposition of antigen-antibody complexes in tissues and blood vessels. These immune complexes activate the complement system and recruit inflammatory cells, leading to tissue injury and inflammation. The clinical manifestations depend on the site of deposition, which can include the kidneys, joints, skin, and blood vessel walls, as seen in conditions like serum sickness and systemic lupus erythematosus.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1183 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/immune-complex-disease/"
}