Intrinsic solubility
Term · Chemistry · MLC-T-CHM-006040
The equilibrium solubility of the un-ionized form of a compound in a given solvent, typically water, at a specific temperature and pH. This value is a fundamental physicochemical property of a substance, independent of pH for ionizable compounds. It is a key parameter in drug discovery and formulation, influencing absorption and bioavailability.
| Identifier | MLC-T-CHM-006040 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1738 (https://doi.org/10.1351/PAC-REC-12-11-23) |
| See also | Equilibrium solubility; Kinetic solubility; Supersaturated solution |
Record as JSON
{
"id": "MLC-T-CHM-006040",
"term": "Intrinsic solubility",
"field": "Chemistry",
"definition": "The equilibrium solubility of the un-ionized form of a compound in a given solvent, typically water, at a specific temperature and pH. This value is a fundamental physicochemical property of a substance, independent of pH for ionizable compounds. It is a key parameter in drug discovery and formulation, influencing absorption and bioavailability.",
"subject": "Chemistry and Human Health",
"see_also": [
"equilibrium solubility",
"kinetic solubility",
"supersaturated solution"
],
"references": [
"PAC, 2013, 85, 1725. 'Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)' on page 1738 (https://doi.org/10.1351/PAC-REC-12-11-23)"
],
"url": "https://mlchart.com/terminology/chemistry/intrinsic-solubility/"
}
Record 6,410 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.