Membrane attack complex

{
  "id": "MLC-T-CHM-007155",
  "term": "Membrane attack complex",
  "field": "Chemistry",
  "definition": "A structure formed on the surface of pathogen cells as part of the complement system, a component of the innate immune response. It consists of multiple complement proteins (C5b, C6, C7, C8, and multiple C9 units) that assemble to create a pore in the target cell's membrane. This pore disrupts the cell's osmotic balance, leading to cell lysis and death.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "target cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1212 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/membrane-attack-complex/"
}