Nondisjunction

{
  "id": "MLC-T-CHM-008018",
  "term": "Nondisjunction",
  "field": "Chemistry",
  "definition": "The improper segregation of chromosomes or chromatids during cell division, leading to an unequal distribution of genetic material into daughter cells. This error can occur during meiosis I, meiosis II, or mitosis. It results in aneuploidy, a condition where cells have an abnormal number of chromosomes, such as in Down syndrome.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "gamete"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 785 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/nondisjunction/"
}