Properdin

{
  "id": "MLC-T-CHM-013439",
  "term": "Properdin",
  "field": "Chemistry",
  "definition": "A plasma protein that stabilizes the C3 convertase of the alternative pathway of the complement system, thereby amplifying complement activation. It binds to C3bBb, preventing its dissociation and extending its half-life, which leads to enhanced deposition of C3b on microbial surfaces. This protein is a positive regulator of the alternative pathway, contributing to innate immunity against pathogens.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "alternative pathway",
    "erythrocyte",
    "euglobulin"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1236 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/properdin/"
}