Pseudo-acceptable daily intake

{
  "id": "MLC-T-CHM-009626",
  "term": "Pseudo-acceptable daily intake",
  "field": "Chemistry",
  "definition": "An intake value for a substance, treated as safe for daily lifelong exposure, that is derived by dividing the lowest dose with an observed effect by a factor of 1000 for non-carcinogenic endpoints. It is used when the data do not support a no-observed-adverse-effect level, so the larger factor stands in for the missing information. It is a cruder estimate than a standard acceptable daily intake, which usually applies a factor of 100 to a no-effect level.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1291 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pseudo-acceptable-daily-intake/"
}