Qa antigen

{
  "id": "MLC-T-CHM-009713",
  "term": "Qa antigen",
  "field": "Chemistry",
  "definition": "A non-classical MHC class I molecule of the mouse, encoded in the Qa region of the H-2 complex, that is expressed on some cell types and is less polymorphic than the classical class I proteins. Instead of presenting a broad range of peptides to T cells, Qa molecules present a restricted set and are recognized by particular receptors on immune cells. Qa-1, which binds the Qdm peptide derived from classical class I leader sequences and engages CD94/NKG2A, is the best-characterized member.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "major histocompatibility complex class I molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1238 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/qa-antigen/"
}