Rotating-frame NOE spectroscopy

{
  "id": "MLC-T-CHM-010417",
  "term": "Rotating-frame NOE spectroscopy",
  "field": "Chemistry",
  "definition": "A nuclear magnetic resonance technique that measures the nuclear Overhauser effect (NOE) in a coordinate system that rotates with the radiofrequency field. This method, also known as ROESY, is used to determine the proximity of protons in molecules by observing cross-relaxation between spins that are locked by a strong radiofrequency field. Unlike standard NOE spectroscopy, ROESY can distinguish between direct and spin diffusion mediated effects, making it applicable to a wider range of molecular sizes.",
  "synonyms": [
    "cross-relaxation appropriate for minimolecules emulated by locked spins (CAMELPSIN)"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "nuclear Overhauser effect spectroscopy",
    "nuclear magnetic resonance spectroscopy",
    "spin-spin relaxation"
  ],
  "references": [
    "PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 703 (https://doi.org/10.1515/pac-2019-0203)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/rotating-frame-noe-spectroscopy/"
}