Sandwich immunoassay

{
  "id": "MLC-T-CHM-010511",
  "term": "Sandwich immunoassay",
  "field": "Chemistry",
  "definition": "A type of immunoassay where the analyte is bound between two antibodies, forming a 'sandwich' complex. One antibody, the capture antibody, is immobilized on a solid support, while the other, the detection antibody, is labeled. This method offers high specificity and sensitivity for detecting antigens, commonly used in ELISA tests.",
  "synonyms": [
    "two-site, noncompetitive immunoassay"
  ],
  "subject": "Analytical Chemistry",
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1142 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/sandwich-immunoassay/"
}