Scatchard equation

{
  "id": "MLC-T-CHM-010555",
  "term": "Scatchard equation",
  "field": "Chemistry",
  "definition": "An equation for ligand binding to a macromolecule that has a set of independent, identical sites, written r/c = K(n minus r), where r is the number of ligand molecules bound per macromolecule, c the free ligand concentration, K the binding constant and n the number of sites. Plotting r/c against r gives a straight line, the Scatchard plot, whose slope is minus K and whose intercept on the r axis gives n; curvature signals cooperativity or more than one class of site.",
  "subject": "Polymer",
  "references": [
    "PAC, 2012, 85, 463. 'Terminology for aggregation and self-assembly in polymer science (IUPAC Recommendations 2013)' on page 484 (https://doi.org/10.1351/PAC-REC-12-03-12)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/scatchard-equation/"
}