Scintillation proximity assay

{
  "id": "MLC-T-CHM-010582",
  "term": "Scintillation proximity assay",
  "field": "Chemistry",
  "definition": "A homogeneous immunoassay technique that measures molecular interactions in solution without the need for separation steps, relying on the proximity of a radiolabeled molecule to a scintillant-containing bead. When the radiolabel binds to a molecule captured on the bead, the emitted radiation excites the scintillant, producing light. This method is widely used in drug discovery for high-throughput screening.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "homogeneous assay"
  ],
  "references": [
    "PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1154 (https://doi.org/10.1351/PAC-REC-09-05-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/scintillation-proximity-assay/"
}