Screen validation

{
  "id": "MLC-T-CHM-010596",
  "term": "Screen validation",
  "field": "Chemistry",
  "definition": "The process of confirming that a high-throughput screening assay is reliable, reproducible, and suitable for identifying active compounds. This involves assessing parameters such as signal-to-noise ratio, Z-factor, and the consistency of results across multiple experiments. Successful validation confirms the assay's ability to discriminate between active and inactive substances.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "assay validation",
    "plate format"
  ],
  "references": [
    "PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1154 (https://doi.org/10.1351/PAC-REC-09-05-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/screen-validation/"
}