Sedimentation velocity method

{
  "id": "MLC-T-CHM-010655",
  "term": "Sedimentation velocity method",
  "field": "Chemistry",
  "definition": "A technique used to determine the molar mass and hydrodynamic properties of macromolecules by observing their rate of sedimentation in an ultracentrifuge. The sample is subjected to a strong centrifugal field, causing the molecules to move outwards at a rate dependent on their size, shape, and density. This method provides information about the sedimentation coefficient and can be used to analyze polydispersity.",
  "subject": "Polymer",
  "see_also": [
    "sedimentation coefficient"
  ],
  "references": [
    "Purple Book, 1st ed., p. 62 (http://old.iupac.org/publications/books/author/metanomski.html)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/sedimentation-velocity-method/"
}