Severe combined immunodeficiency

{
  "id": "MLC-T-CHM-010784",
  "term": "Severe combined immunodeficiency",
  "field": "Chemistry",
  "definition": "A group of rare, inherited disorders characterized by a profound defect in both T lymphocyte and B lymphocyte function, leading to a severely compromised immune system. Individuals with SCID are highly susceptible to recurrent, severe infections. Without treatment, such as bone marrow transplantation, it is often fatal in infancy.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "immunodeficiency",
    "T lymphocyte"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1244 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/severe-combined-immunodeficiency/"
}