Bare lymphocyte syndrome

{
  "id": "MLC-T-CHM-001113",
  "term": "Bare lymphocyte syndrome",
  "field": "Chemistry",
  "definition": "A rare, inherited immunodeficiency disorder characterized by the inability of immune cells to express major histocompatibility complex (MHC) class I or class II molecules on their surface. This defect severely impairs the immune system's ability to present antigens to T lymphocytes, leading to recurrent, severe infections. It is classified into two main types based on the affected MHC class.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "major histocompatibility complex class II molecule",
    "immunodeficiency",
    "major histocompatibility complex class I molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1133 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/bare-lymphocyte-syndrome/"
}