Sphingolipid

{
  "id": "MLC-T-CHM-011192",
  "term": "Sphingolipid",
  "field": "Chemistry",
  "definitions": [
    "A lipid built on a sphingoid base, a long-chain aliphatic amino alcohol such as sphingosine, usually with a fatty acid joined to its amino group to give ceramide, the core of the complex sphingolipids. Adding a phosphocholine head yields sphingomyelin, and adding sugars yields glycosphingolipids such as cerebrosides and gangliosides. They are abundant in the membranes of nervous tissue, and sphingosine-1-phosphate is a signaling lipid.",
    "A class of lipids characterized by a backbone of sphingoid bases, a set of aliphatic amino alcohols. These compounds are integral components of cell membranes, particularly abundant in nervous tissue. They play roles in cell recognition and signaling, with ceramide being a fundamental building block."
  ],
  "subject": [
    "Chemistry and Human Health",
    "Analytical Chemistry"
  ],
  "see_also": [
    "ceramide",
    "sphingosine",
    "fatty acyls",
    "glycerophospholipids"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 906 (https://doi.org/10.1515/pac-2015-0103)",
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1182 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/sphingolipid/"
}