Steroid 21-monooxygenase

{
  "id": "MLC-T-CHM-011402",
  "term": "Steroid 21-monooxygenase",
  "field": "Chemistry",
  "definition": "An enzyme, also known as 21-hydroxylase, that catalyzes the hydroxylation of steroids at the C-21 position. This reaction is a step in the biosynthesis of mineralocorticoids and glucocorticoids, such as aldosterone and cortisol, from progesterone and 17-hydroxyprogesterone. Deficiencies in this enzyme lead to congenital adrenal hyperplasia.",
  "synonyms": [
    "21-hydroxylase"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "hormone",
    "steroid"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 809 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/steroid-21-monooxygenase/"
}