Th0 cell
Term · Chemistry · MLC-T-CHM-011913
A helper T lymphocyte that has been activated but not yet committed to a subset, so it secretes a broad mix of cytokines such as IL-2, IL-4, and interferon-gamma rather than the restricted profile of Th1 or Th2 cells. It acts as a precursor that can polarize into Th1, Th2, Th17, or regulatory subsets according to the cytokines present. Unlike a naive CD4 cell, which secretes little cytokine before activation, it already produces cytokines.
| Identifier | MLC-T-CHM-011913 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1250 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | Graves disease; Helper T lymphocyte; Sjögren syndrome; Th1 cell; Th2 cell; Cytokine; Rheumatoid arthritis |
Record as JSON
{
"id": "MLC-T-CHM-011913",
"term": "Th0 cell",
"field": "Chemistry",
"definition": "A helper T lymphocyte that has been activated but not yet committed to a subset, so it secretes a broad mix of cytokines such as IL-2, IL-4, and interferon-gamma rather than the restricted profile of Th1 or Th2 cells. It acts as a precursor that can polarize into Th1, Th2, Th17, or regulatory subsets according to the cytokines present. Unlike a naive CD4 cell, which secretes little cytokine before activation, it already produces cytokines.",
"subject": "Chemistry and Human Health",
"see_also": [
"Graves disease",
"helper T lymphocyte",
"Sjögren syndrome",
"Th1 cell",
"Th2 cell",
"cytokine",
"rheumatoid arthritis"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1250 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/th0-cell/"
}
Record 12,708 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.