Th1 cell

{
  "id": "MLC-T-CHM-011914",
  "term": "Th1 cell",
  "field": "Chemistry",
  "definition": "A subtype of helper T lymphocyte, designated as type 1, that directs cell-mediated immunity primarily against intracellular pathogens like bacteria and viruses. These cells produce a characteristic set of cytokines, most notably interferon-gamma (IFN-γ), which activates macrophages and cytotoxic T cells. Dysregulation of the Th1 response is associated with certain organ-specific autoimmune conditions, such as Crohn disease.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Crohn disease",
    "Hashimoto thyroiditis",
    "helper T lymphocyte",
    "Th2 cell",
    "autoimmune disease",
    "cytotoxic T lymphocyte",
    "diabetes mellitus type 1",
    "intercellular adhesion molecule",
    "interleukin",
    "macrophage",
    "phagocyte",
    "lymphotoxin"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1250 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/th1-cell/"
}