Vetoing

{
  "id": "MLC-T-CHM-013690",
  "term": "Vetoing",
  "field": "Chemistry",
  "definition": "A mechanism of immune tolerance in which a veto cell that carries a self peptide on its MHC molecules kills, by inducing apoptosis, any lymphocyte whose receptor recognizes that peptide-MHC complex. Cells described as having veto activity include CD8-positive T cells, natural killer cells and some stem and dendritic cells. The result is deletion of the recognizing clone, not general suppression of immune activity.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "lymphocyte",
    "major histocompatibility complex molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1259 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/vetoing/"
}