Antagonism

{
  "id": "MLC-T-CHM-000650",
  "term": "Antagonism",
  "field": "Chemistry",
  "definition": "A situation in which the combined toxic effect of two or more chemicals is less than the sum of their individual effects when administered separately. In toxicology, this interaction results in a reduction of the expected toxicity. For example, functional antagonism occurs when two chemicals produce opposite effects on the same physiological function, while chemical antagonism involves a reaction between the substances that neutralizes one or both.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "synergism"
  ],
  "references": [
    "PAC, 1993, 65, 2003. 'Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)' on page 2014 (https://doi.org/10.1351/pac199365092003)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/antagonism/"
}