Chromatolysis

{
  "id": "MLC-T-CHM-002048",
  "term": "Chromatolysis",
  "field": "Chemistry",
  "definition": "A pathological process involving the dissolution and dispersion of Nissl bodies (rough endoplasmic reticulum and ribosomes) within the cytoplasm of a neuron. This change typically occurs in response to axonal injury or certain neurodegenerative diseases. Chromatolysis is a reversible process that reflects an increased metabolic demand for protein synthesis during neuronal repair.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Nissl body"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 857 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/chromatolysis/"
}