MLchartDataset catalogue

Transporters associated with antigen processing

Term · Chemistry · MLC-T-CHM-012265

A heterodimeric protein complex, TAP1 and TAP2, located in the membrane of the endoplasmic reticulum. This complex actively transports antigenic peptides from the cytosol into the endoplasmic reticulum lumen. There, the peptides bind to major histocompatibility complex class I molecules for presentation on the cell surface.

Table 1. Record
IdentifierMLC-T-CHM-012265
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1255 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoAntigenic; Major histocompatibility complex class I molecule
Record as JSON
{
  "id": "MLC-T-CHM-012265",
  "term": "Transporters associated with antigen processing",
  "field": "Chemistry",
  "definition": "A heterodimeric protein complex, TAP1 and TAP2, located in the membrane of the endoplasmic reticulum. This complex actively transports antigenic peptides from the cytosol into the endoplasmic reticulum lumen. There, the peptides bind to major histocompatibility complex class I molecules for presentation on the cell surface.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "antigenic",
    "major histocompatibility complex class I molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1255 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/transporters-associated-with-antigen-processing/"
}

Record 13,077 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.