Correlation spectroscopy

{
  "id": "MLC-T-CHM-002603",
  "term": "Correlation spectroscopy",
  "field": "Chemistry",
  "definition": "A homonuclear two-dimensional NMR experiment, abbreviated COSY, in which a cross peak appears at the shift coordinates of two nuclei whenever they are linked by spin-spin coupling, usually across two or three bonds. The diagonal carries the ordinary one-dimensional spectrum and the off-diagonal peaks map which protons are coupled. In contrast to NOESY, whose cross peaks come from through-space proximity, COSY peaks come from through-bond coupling.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "correlation spectroscopy through long-range coupling",
    "two-dimensional nuclear magnetic resonance spectroscopy"
  ],
  "references": [
    "PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 684 (https://doi.org/10.1515/pac-2019-0203)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/correlation-spectroscopy/"
}