Cre/loxP

{
  "id": "MLC-T-CHM-002669",
  "term": "Cre/loxP",
  "field": "Chemistry",
  "definition": "A site-specific recombination system derived from bacteriophage P1, widely used in molecular biology to induce targeted genetic modifications in living organisms. The Cre recombinase enzyme recognizes specific loxP sites and mediates recombination between them, leading to excision, inversion, or translocation of DNA segments. This system is instrumental in creating conditional gene knockouts in mice.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 740 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cre-loxp/"
}