Danger hypothesis

{
  "id": "MLC-T-CHM-002855",
  "term": "Danger hypothesis",
  "field": "Chemistry",
  "definition": "A theory proposing that the immune system responds primarily to signals of cellular damage or 'danger' rather than simply to foreignness. This hypothesis suggests that the immune system is activated by molecules released from stressed or injured cells, regardless of whether the cells are self or non-self. It provides an alternative framework for understanding immune responses, including autoimmunity.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "idiosyncratic drug reaction"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1155 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/danger-hypothesis/"
}