Intrinsic factor

{
  "id": "MLC-T-CHM-006031",
  "term": "Intrinsic factor",
  "field": "Chemistry",
  "definition": "A glycoprotein secreted by the parietal cells of the stomach lining that binds to vitamin B12, also known as cobalamin. This binding forms a complex that facilitates the vitamin's subsequent absorption in the terminal ileum. A deficiency of intrinsic factor, caused by autoimmune conditions or gastric surgery, leads to pernicious anemia.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1247 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/intrinsic-factor/"
}